Immunosuppressant Drug Testing Controls and Calibrators
Abcam Everolimus, mTOR inhibitor, 25MG
MW 958.2 Da, Purity >98%. Potent mTOR inhibitor (IC₅₀ = 1.6 - 2.4 nM). Immunosupressant and anticancer activity in vivo. Orally active.
The product is subject to the following: Abcam Restricted Use Statement
AdipoGen Amikacin disulfate salt
Chemical. CAS 39831-55-5. Formula C22H43N5O13 . 2H2SO4. MW 781.76. Amikacin is a broad-spectrum aminoglycoside antibiotic and a semisynthetic analog of kanamycin. It irreversibly binds to 16S rRNA and the RNA-binding S12 protein of the 30S subunit and 50S subunit of prokaryotic ribosome and inhibits protein synthesis. It works in a concentration-dependent manner, and has better action in an alkaline environment. Amikacin disulfate is very active against most Gram-negative bacteria including gentamicin- and tobramycin-resistant strains, due to its resistance to inactivating enzymes. Amikacin disulfate also inhibits the infections caused by susceptible Nocardia and nontuberculous mycobacteria. Amikacin can be used to treat non-tubercular mycobacterial infections and tuberculosis when first-line drugs fail to control the infection.
Medchemexpress LLC Everolimus Solution 10 mM * 1 mL in DMSO
Everolimus (RAD001) is a Rapamycin (HY-10219) derivative and a potent, selective and orally active mTOR1 inhibitor. Everolimus binds to FKBP-12 to generate an immunosuppressive complex. Everolimus inhibits tumor cells proliferation and induces cell apoptosis and autophagy. Everolimus has potent immunosuppressive and anticancer activities.
Abcam Everolimus, mTOR inhibitor, 5MG
MW 958.2 Da, Purity >98%. Potent mTOR inhibitor (IC₅₀ = 1.6 - 2.4 nM). Immunosupressant and anticancer activity in vivo. Orally active.
The product is subject to the following: Abcam Restricted Use Statement
